Ịdị ọcha dị elu 540737-29-9 Tofacitinib citrate maka JAK Pathway Inhibitor egosipụtara

Nnukwu ịdị ọcha 540737-29-9 Tofacitinib citrate maka JAK Pathway Inhibitor

Nkọwa dị mkpirikpi:

Ịdị ọcha:≧99.0%

Ọkọlọtọ Ogo:Standardkpụrụ Enterprise ma ọ bụ dị ka achọrọ

Ike:35Kgs/ọnwa

Ndụ nchekwa:Afọ atọ

Ngwa:Na-agwọ ọrịa ogbu na nkwonkwo, psoriatic ogbu na nkwonkwo, ankylosing spondylitis na ulcerative colitis.

Uru otu:Ahụmahụ mbupụ ahịa otu na ọkachamara ọzụzụ na factory

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Nkọwa ngwaahịa

FAQ

Mkpado ngwaahịa

Ngwaahịaaha	Citrate nke Tofacitinib
Ụdị okwu	(3R,4R) -1- (Cyanoacetyl) -4-methyl-N-methyl-N-1H-pyrrolo [2,3-d] pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3 - propanetricarboxylate;CP 690500-10;CP 690550-10;(3R,4R) -4-Methyl-3- (methyl-7H-pyrrolo [2,3-d] pyrimidin-4-ylamino) -beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate
CAS Mba.	540737-29-9
Ọdịdị	Gbanyụọ ọcha na ntụ ntụ ọcha
Usoro ihe omimi	C₁₆H₂₀N₆OC₆H₈O₇
Ibu molekụla	504.50
Ngwa	Ọkwa ọgwụ ma ọ bụ ebumnuche nyocha
Nkwakọ ngwaahịa	Dị ka arịrịọ gị si dị
Nchekwa	Chekwaa n'ime akpa siri ike, nke na-enweghị ọkụ n'ebe dị mma

Tofacitinib Citrate (CAS #540737-29-9)
NGWA	Ọkọlọtọ	Nsonaazụ
Ọdịdị	Gbanyụọ ọcha na ntụ ntụ ọcha	Gbanyụọ ntụ ntụ ọcha
njirimara	HPLC;IR;HNMR	Na-akwado
Solubility	Soluble na DMSO na 100mg / ml, soluble nke ukwuu na ethanol, obere soluble na mmiri wdg.	Na-akwado
Ọnwụ na ihicha	≤0.5%	0.12%
Ihe fọdụrụ na mgbanye	≤0.1%	0.05%
Ọla dị arọ	≤10ppm	Na-akwado
Ihe ndị emetụtara	Diasteromer (RS+SR) ≤0.1% Otu adịghị ọcha ≤0.15% Mkpokọta adịghị ọcha ≤1.0%	0.05% 0.14% 0.18%
Enantiomorphism Isomers	≤0.2%	Na-akwado
Ihe mgbaze fọdụrụnụ	Ethanol ≤5000ppm Methanol ≤3000ppm Toluene ≤890ppm	Na-akwado
Citrate ọdịnaya	36.2% ~ 40%	37.8%
Ịdị ọcha	≥99.0%	99.38%
Nyocha	60.68% ~ 63.16% nke Tofacitinib INN 98% ~ 102% nke Tofacitinib Citrate INN	62.04% 99.12%
Mmechi: Emebere ya

Ozi ụlọ ọrụ

√ Ahụmahụ zuru oke nke oyi akwa na ụlọ ọrụ mmepụta ihe na ndị na-eso ụzọ teknụzụ nwere nkà;
√ Quality bụ mgbe anyị n'elu echiche, siri ike QC usoro;
√ 11 afọ nwere ahụmahụ mbupụ ahịa otu;
√ ụlọ nyocha R&D nọọrọ onwe ya;
√ Ụlọ ọrụ GMP abụọ bịanyere aka na ogologo oge;
√ Akụ bara ụba nke ọtụtụ ụlọ ọrụ na-abaghị uru maka ọrụ ahaziri iche;
√ Ndị otu na-arụ ọrụ nke ọma na ụzọ na-agbanwe agbanwe.
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